Saturday, September 21

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Main Topic:

New system biologic therapeutic concepts: from dietetics to Molecular System and Immune Therapy

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08:30 Registration

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09:00 – 10:30

Dr. med. Jürgen Aschoff

Vitamin D receptor deactivation – A challenge for diagnostics and therapy

The health-supporting effect of vitamin D is undisputed. Yet the significance of microbe-induced deactivation of vitamin D receptors for immunological regulation and effector functions is much less known. The presentation covers how receptor blockages influence health preservation within the organism, how these can be clinically diagnosed, and which therapeutic strategies are available to overcome them.

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10:45 – 12:15

Dr. med. Kirsten Beurer

The intestinal microbiome – the unknown cosmos

For a long time, intestines were reduced to purely digestive functions by conventional medicine. Even the role of intestinal flora in vitamin production remained underrated. Scientists and therapists, who pointed out the enormous relevance of a “healthy intestine” for preventing diseases, were usually taken for fools. Yet a few years ago, this image began to change for good. Nowadays, we see an exponentially increasing amount of scientific studies on the microbiome indicating the relevance of an intact intestinal flora for the preservation of a healthy organism. This presentation shall not only examine the newest findings regarding the microbiome and its complex interaction with other organ systems, but it shall also depict different therapeutic application options of the microbiome to optimize long-run Health Medicine.

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12:15 – 14:00

Lunch Break

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14:00 – 15:30

Dr. med. Marc Azemar

Oncoimmune therapy – up to date

The presentation provides an overview on current and future oncoimmunologic therapeutic strategies. Special focus points of the presentation are the use of antibodies against CTLA-4 and PD- 1, as well as innovative cell-therapeutic therapy schemes. It shall also illustrate further on the basic immunological mechanisms of oncoimmune therapies as well as discuss the newest clinical studies on the matter.

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15:45 – 17:15

Dr. med. Olaf Kuhnke

Fibromyalgia – Fundamentals and new aspects of biological therapy

This medical condition is a complex matter which remains mostly unexplained. The absence of “hard“ data from imaging or lab techniques and the existence of unspecific accompanying phenomena often lead to misinterpretations and to a delayed proper therapeutic response. This presentation covers relevant fundamentals from the clinical, diagnostic and pain therapy fields, while also enlightening on little-noticed pain pacemaker factors of its complex course of disease and possible ways out of this chronic problem. Besides traditionally physical and typical medicinal strategies, the speaker shall address the subjects “diagnosing a focus, removing interference fields, and metabolic and hormonal correction” as well as “new electrophysical therapy methods” and “biologic cellular therapeutic support”.

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17:15 – 18:00

Prof. Dr. med. Ivan Rolik

Therapeutic efficacy of complex cell peptide therapy on skin cancer

The presentation covers diverse clinical cases on the successful treatment of skin cancer patients in a private clinic in Moscow, targeting the very positive therapeutic influence of a combined therapy composed of cell peptides and photodynamic therapy.

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from 18:00

„Get-together“ at the Hildegard Garden – Get to know each other and exchange of experiences

Taste the wines of our region!
Weingut Hemmes, Bingen

Sunday, September 22

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Leonardis Foundation Health Forum

Relevance of molecular and cellular homeostasis for the reproduction and preservation of healthy life processes

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08:30 Admission

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09:00 – 10:00

Prof. Dr. rer. nat. Michael Huber

Homeostasis – a central ground principle of salutogenesis

Homeostasis is the principle by which organisms are capable of preserving a physiologically reasonable (flow) balance in the presence of changing environmental conditions. The regulatory cycles theory can serve as a model for this. The chronic loss of homeostasis is frequently related to the development of chronic diseases, such as cancer or type-II diabetes, and can be already proven at cellular level. Some causes for this are, for example, the deactivation of negative-regulating control elements (proteins), or the chronic off-setting of activating mechanisms, which then withdraw themselves from the regulated control system. These mechanisms can be exemplified through chronic inflammatory diseases and tumor growth.

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10:15 – 11:15

Dr. rer. nat. Felix Kratz

Mast cell activation syndrome (MCAS) – “immunologic guard cells in dysbalance“

The mast cell activation syndrome is a disease of the immunological system in which dysregulated mast cells react disproportionately to environmental stimuli, thus leading to a range of acute life-threatening, but also long-term, chronic, clinical symptoms. Cardiovascular, dermatological, gastrointestinal, neurological and respiratory symptom constellations are usually related to this. The prevalence of said syndrome in the global population is estimated to be at 5% to 17%, showing a growing tendency. This presentation shall illustrate the pathogenesis of MCAS and its possible treatment strategies in depth.

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Research Forum:

Molecular System and Immune Therapy

11:30 – 12:30

Dr. med. Bernd Hildenbrand

Molecular System and Immune Therapy (MOSIT) – What is new?

The presentation seeks to build a bridge between the fundamentals of Transplantation Medicine and Endocrinology and the newest findings of regenerative and immunologic- oriented (pre-)clinical research. This does not only act as the base for the development of innovative therapy strategies and biologics for the successful treatment of chronic diseases, but it also contributes to long-lasting health support.

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12:30 – 14:00

Lunch Break

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14:00 – 14:45

Dr. rer. nat. Michaela Endres

Project I: Study on the regeneration of bone and cartilage tissue

Presentation on the first research findings from the research project “Study on the effect of lyophilisates and ultrafiltrates gained from fetal organ tissue of xenogeneic origin on in-vitro migration, proliferation and differentiation of expanded human cartilage cells, precursor bone cells and mesenchymal stem cells.

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15:00 – 15:45

Dr. rer. nat. Matthias Domogalla

Project II: Study on the antitumor efficacy, maturation and polarization of dendritic cells

Within the framework of this presentation, the first in-vitro research results on antitumor efficacy and maturation of human dendritic cells after the application of clinic-compliantly produced lyophilized xenogeneic fetal tissue or ultrafiltrates gained from it are illustrated and discussed from a medical-scientific context.

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15:45 – 16:00

Summary & Final Diskussion Round

Dr. med. Jürgen Aschoff

• Practice for General Medicine and Naturophatics in Wuppertal
• Fields of expertise: general and health medicine, naturopathics, research on metagenome and vitamin-D receptors

Dr. med. Marc Azemar

• Centre Paul Strauss in Strasbourg
• Fields of expertise: Internal Medicine, Haematology and Health Medicine, Initiation and Direction of Clinical Studies

Dr. phil. nat. Kirsten Beurer

• Biologist and doctorate biochemist
• Continuing Education and Scientific Consulting
• Fields of expertise: Phytotherapy, Orthomolecular and Mitochondrial Medicine, Health Medicine

Dr. rer. nat. Felix Kratz

• CytRx Corporation and Centurion BioPharm Corporation
• Fields of expertise: pre-clinical and clinical cancer research, development of innovative, targeted (bio) therapeuticals

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Further speakers:

• Dr. rer. nat. Matthias Domogalla
• Dr. rer. nat. Michaela Endres
• Dr. med. Bernd Hildenbrand
• Prof. Dr. rer. nat. Michael Huber
• Dr. med. Olaf Kuhnke
• Prof. Dr. med. Ivan Rolik

Programme Brochure as PDF: